BDBM50613899 CHEMBL5278109

SMILES CCn1ncc2cc(ccc12)-c1nc(NCc2cccc(F)c2)[nH]c1-c1cccc(C)n1

InChI Key InChIKey=APYPVBDMPHIBGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613899   

TargetTGF-beta receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613899(CHEMBL5278109)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of ALK5 in human Hs-578T cells assessed as effect of TGF-beta-induced Smad3/4 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetActivin receptor type-1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50613899(CHEMBL5278109)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ALK2 by NanoBERT assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed