BDBM50613683 CHEMBL5270270

SMILES COc1cc2ncnc(NCCOc3ccccc3F)c2cc1OC

InChI Key InChIKey=SQUSZMTZUQQFKO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50613683   

TargetBromodomain-containing protein 4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613683(CHEMBL5270270)
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibition of BRD4 (unknown origin) using pre-acetylated Biotin-Histone 4 Peptide as substrate by alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613683(CHEMBL5270270)
Affinity DataIC50: 44nMAssay Description:Inhibition of EGFR (unknown origin) using flurogenic substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613683(CHEMBL5270270)
Affinity DataIC50: 8.73E+3nMAssay Description:Inhibition of human recombinant ERBB2 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613683(CHEMBL5270270)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed