BDBM50613680 CHEMBL5285509

SMILES CC(C)n1nc2ncnc(N)c2c1C1C=c2cc(O)ccc2=N1

InChI Key InChIKey=ULTBPCMFBBBUND-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50613680   

TargetBromodomain-containing protein 4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613680(CHEMBL5285509)
Affinity DataKd:  1.74E+3nMAssay Description:Binding affinity to human recombinant BRD4 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613680(CHEMBL5285509)
Affinity DataIC50: 410nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613680(CHEMBL5285509)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50613680(CHEMBL5285509)
Affinity DataIC50: 8nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed