BDBM50613320 CHEMBL5283120

SMILES [2H]C1([2H])CC[C@@]2(COc3nc(N4CC5CCC4CN5)c4cnc(c(F)c4n3)-c3cc(O)cc(F)c3C3CC3)C[C@@]([2H])(F)CN12

InChI Key InChIKey=WJAWZBCVLSFKBG-WYGZXHLZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50613320   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50613320(CHEMBL5283120)
Affinity DataIC50: 50nMAssay Description:Inhibition of human KRAS G12D mutant in human AGS cells assessed as reduction in phosphorylated ERK level incubated for 3 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed