BDBM50613309 CHEMBL5278418

SMILES O=C1NCCCCCNc2nccc(Nc3cc1[nH]n3)n2

InChI Key InChIKey=LFAOBOWYZYMDBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50613309   

TargetBone morphogenetic protein receptor type-2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613309(CHEMBL5278418)
Affinity DataIC50: 630nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613309(CHEMBL5278418)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length GSK3A (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of tracer K8 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613309(CHEMBL5278418)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length intact GSK3B (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613309(CHEMBL5278418)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length lysed GSK3B (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed