BDBM50612980 CHEMBL5275910

SMILES COC[C@@H](NC(=O)C1(C)CCCCC1)C(=O)Nc1nnc(Cc2ccc(cc2)[N+]([O-])=O)s1

InChI Key InChIKey=TZHJMISTQRDJHE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612980   

TargetUbiquitin carboxyl-terminal hydrolase 21(Human)
Bayer

Curated by ChEMBL

LigandBDBM50612980(CHEMBL5275910)Copy SMILESCopy InChI

Affinity DataIC50: 74nMAssay Description:Inhibition of human full length USP21 using Btn-Ahx-PNIRFLD-K(Ubi)-LPQQT-GD-amide as substrate preincubated for 15 to 20 mins followed by substrate a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
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TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
Bayer

Curated by ChEMBL

LigandBDBM50612980(CHEMBL5275910)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human His-tagged USP2 (259 to 605 residues) using ubiquitin rhodamine 110 110 as substrate preincubated for 15 to 20 mins followed by e...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL