BDBM50611549 CHEMBL5273782::US20240246937, Example 358B

SMILES O=C1N(Cc2cc(no2)-c2ccccc2)CCN(C2CCCC2)C1=O

InChI Key InChIKey=XDVJXSKUNOKZTL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611549   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611549(CHEMBL5273782 | US20240246937, Example 358B)
Affinity DataEC50:  2nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611549(CHEMBL5273782 | US20240246937, Example 358B)
Affinity DataEC50:  1nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetL-amino-acid oxidase(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50611549(CHEMBL5273782 | US20240246937, Example 358B)
Affinity DataEC50:  2nMAssay Description:Inhibition of C-terminal 6-His tagged recombinant human IL4I1 (Gln22 to His567 residues) expressed in CHO cells using Phe/Tyr/Trp as substrate assess...More data for this Ligand-Target Pair
In DepthDetails
PubMed