BDBM50611548 CHEMBL5272632::US20240246937, Example 279

SMILES O=C1N(Cc2ncc(cn2)-c2ccccc2)CCN(C2CCOC2)C1=O

InChI Key InChIKey=IUCNCJOMQSYXPI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50611548   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611548(CHEMBL5272632 | US20240246937, Example 279)
Affinity DataEC50:  68nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
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TargetL-amino-acid oxidase(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50611548(CHEMBL5272632 | US20240246937, Example 279)
Affinity DataEC50:  68nMAssay Description:Inhibition of C-terminal 6-His tagged recombinant human IL4I1 (Gln22 to His567 residues) expressed in CHO cells using Phe/Tyr/Trp as substrate assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed