BDBM50611061 CHEMBL5291234

SMILES O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1

InChI Key InChIKey=OBERVORNENYOLE-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50611061   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMAssay Description:Inhibition of full-length His-tagged METTL3/full length FLAG-tagged METTL14 (unknown origin) expressed in baculovirus expression system using synthet...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to full-length His-tagged METTL3/full length FLAG-tagged METTL14 (unknown origin) expressed in baculovirus expression system assesse...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Swansea University

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length His-tagged METTL3 in baculovirus expression system (unknown origin) measured by mass spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Swansea University

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Swansea University

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to METTL3 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed