BDBM50610910 CHEMBL5280844

SMILES OC[C@@H]1CCC(CO1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12

InChI Key InChIKey=JSFCZQSJQXFJDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50610910   

TargetTyrosine-protein kinase Lck(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610910(CHEMBL5280844)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610910(CHEMBL5280844)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of BTK C481S mutant (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProtein-tyrosine kinase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610910(CHEMBL5280844)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Yes(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610910(CHEMBL5280844)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed