BDBM50609146 CHEMBL5273263

SMILES CC[C@](C)(O)C#Cc1cc2n(ncc2cn1)-c1ccnc(N)n1

InChI Key InChIKey=WZLQQYUWMGFXDE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50609146   

TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609146(CHEMBL5273263)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609146(CHEMBL5273263)
Affinity DataIC50: 259nMAssay Description:Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTau-tubulin kinase 2(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609146(CHEMBL5273263)
Affinity DataIC50: 13nMAssay Description:Inhibition of TTBK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50609146(CHEMBL5273263)
Affinity DataIC50: 675nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50609146(CHEMBL5273263)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails
PubMed