BDBM50608076 CHEMBL5281547

SMILES Nc1nc2c(O)cc(Br)cc2s1

InChI Key InChIKey=BDPNQSDLTBROFQ-UHFFFAOYSA-N

Data  3 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50608076   

TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of NSD1 (unknown origin) by ITC assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataKd:  1.04E+4nMAssay Description:Inhibition of NSD1 (unknown origin) by ITC assay assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataKd:  1.00E+7nMAssay Description:Binding affinity to NSD1 SET domain(1852 to 2085 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by ITC analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataIC50: 6.60E+7nMAssay Description:Inhibition of NSD1 SET domain (1852 to 2105 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) preincubated for 1 hrs followed by HM...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of N-terminal hexa-histidine tagged NSD1 SET domain (1852 to 2105 residues) (unknown origin) expressed in Escherichia coli incubated for 2...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50608076(CHEMBL5281547)
Affinity DataKd:  1.04E+4nMAssay Description:Binding affinity to hexa-histidine tagged NSD1 SET domain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed