BDBM50607594 CHEMBL5219204

SMILES Clc1cccc(c1)C1(CCCC1)C(=O)N1CCC[C@@H]1C(=O)Nc1cnc2[nH]ncc2c1

InChI Key InChIKey=RAXQFMWVZJPWSR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607594   

TargetHistone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607594(CHEMBL5219204)
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607594(CHEMBL5219204)
Affinity DataEC50:  3.16E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed