BDBM50606979 CHEMBL5219572

SMILES FC(F)(F)c1ccc(cc1)-c1ccc(-[#8]-[#6]-c2ccc(Cl)cc2)c(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)c1

InChI Key InChIKey=QTTHMNQOPULTCO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606979   

TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpA using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606979(CHEMBL5219572)
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed