BDBM50605644 CHEMBL5209093::US11981669, Comparative Example 3
SMILES OC(=O)CNC(=O)c1nc(Br)c2cc(Oc3ccccc3)ccc2c1O
InChI Key InChIKey=MOOCHEISIIMJAU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50605644
TargetThyroid hormone receptor alpha(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Agonist activity at wild type human TR alpha LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of N-terminal biotinylated coactivato...More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Human)
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Guangzhou Institutes of Biomedicine and Health
Curated by ChEMBL
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotin...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of PHD2 (unknown origin) incubated for 15 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 452nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
Affinity DataIC50: 951nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair
Affinity DataIC50: 544nMAssay Description:VHL/elongin B/elongin C were constructed, expressed and purified, and VHL was labeled. PHD1, PHD2 and PHD3 were constructed, expressed and purified. ...More data for this Ligand-Target Pair