BDBM50604981 CHEMBL5197224

SMILES CCCN1CCN(CC1)c1cccc(c1)C1CCCCN1C(=O)OCc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=QLNOSQWPXXWXIP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604981   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50604981(CHEMBL5197224)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in human HEK293T cells assessed as inhibition constant by radioligand com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50604981(CHEMBL5197224)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in human HEK293T cells assessed as inhibition constant by radioligand com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50604981(CHEMBL5197224)
Affinity DataKi:  75nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor/TMEM97 transfected in human HEK293T cells assessed as inhibition constant in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50604981(CHEMBL5197224)
Affinity DataKi:  76nMAssay Description:Displacement of [3H](+)-ditolylguanidine from human sigma 2 receptor/TMEM97 transfected in human HEK293T cells assessed as inhibition constant in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed