BDBM50604326 CHEMBL5188306

SMILES CC(C)(C)NC(=O)CC[C@H](NC(=O)CCNC(=O)C(=C\c1ccc(Cl)cc1)\C#N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1cccc2ccccc12

InChI Key InChIKey=KUYNBCHRXOFGOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604326   

TargetProteasome subunit beta type-8(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604326(CHEMBL5188306)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604326(CHEMBL5188306)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of 20S proteasome subunit beta-5c (unknown origin) using Ac-WLA-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed