BDBM50604320 CHEMBL5204032

SMILES Cc1ccc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)NC(C)(C)C)NC(=O)CCNC(=O)C(=C\c2ccc(C)cc2)\C#N)cc1

InChI Key InChIKey=YVHQRSUVQDQTHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604320   

TargetProteasome subunit beta type-8(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604320(CHEMBL5204032)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50604320(CHEMBL5204032)
Affinity DataIC50: 46nMAssay Description:Inhibition of 20S proteasome subunit beta-5c (unknown origin) using Ac-WLA-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed