BDBM50604186 CHEMBL5199623

SMILES COCCN(C)c1cc(F)c(Nc2n[nH]c3ccc(O[C@H](C)c4c(Cl)cncc4Cl)cc23)c(NC(=O)C=C)c1

InChI Key InChIKey=ZWSVSRSYWXWBNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604186   

TargetFibroblast growth factor receptor 4(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604186(CHEMBL5199623)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using Tyr 04 peptide as substrate i...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604186(CHEMBL5199623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 25 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604186(CHEMBL5199623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 5 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604186(CHEMBL5199623)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 75 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed