BDBM50604174 CHEMBL5169754

SMILES C[C@@H](Oc1ccc2[nH]nc(Nc3c(NC(=O)C=C)cccc3C3CC3)c2c1)c1c(Cl)cncc1Cl

InChI Key InChIKey=OWBVXWHFLPZRAW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604174   

TargetFibroblast growth factor receptor 4(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604174(CHEMBL5169754)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using Tyr 04 peptide as substrate i...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604174(CHEMBL5169754)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 25 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604174(CHEMBL5169754)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 5 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetFibroblast growth factor receptor 3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604174(CHEMBL5169754)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 75 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed