BDBM50604105 CHEMBL5208454

SMILES ClCCC(=O)Nc1ccc2ncnc(Nc3ccc4[nH]cc(Br)c4c3)c2c1

InChI Key InChIKey=WTWFBKFNVCFROY-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50604105   

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFR-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of wild-type EGFR (14 to 721 residues) (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human EGFR L858R/T790M double mutant using GGMEDIYFEFMGG as substrate in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 75nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 2nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPH-A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Flt-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604105(CHEMBL5208454)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed