BDBM50603803 CHEMBL5193501

SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@@H]1C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSCc2cccc(CSC1(C)C)c2)C(N)=O

InChI Key InChIKey=GUWAZMLXUQIQKT-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50603803   

TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataIC50: 244nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataIC50: 628nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataIC50: 94nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataEC50:  618nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603803(CHEMBL5193501)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed