BDBM50603801 CHEMBL5203580

SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CSCc2cccc(CSC[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](Cc3c[nH]cn3)NC1=O)C(N)=O)c2

InChI Key InChIKey=YBWGYSWBATYFBD-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50603801   

TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50: 9.10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataEC50:  902nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataEC50:  915nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50603801(CHEMBL5203580)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as maximal intracellular cAMP accumulation by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed