BDBM50603678 CHEMBL5202351

SMILES CC(C)C[C@H](N)c1cc(C#N)c2cc(ccc2n1)-c1ccncc1

InChI Key InChIKey=FMNWOBLAZAYOSG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50603678   

TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 19nMAssay Description:Inhibition of full length human AAK1 expressed in HEK293F incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBMP-2-inducible protein kinase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 161nMAssay Description:Inhibition of BIKE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 998nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 112nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 57nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 16(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50603678(CHEMBL5202351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MPSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed