BDBM50602840 CHEMBL5182870

SMILES Nc1ccccc1NC(=O)c1ccc(CN2CCC\C(=C/c3ccccn3)C2=O)cc1

InChI Key InChIKey=NBUJRTVDQYEPKP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602840   

TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50: 85nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50: 168nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50: 443nMAssay Description:Inhibition of HDAC3 (unknown origin) using RHKK(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602840(CHEMBL5182870)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC fluorogenic peptide as substrate preincubated for 10 mins followed by substrate addition f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed