BDBM50602398 CHEMBL5198935

SMILES CCCC1CNCc2c1[nH]c(=O)c(C#N)c2N1CCC2(CC2)CC1

InChI Key InChIKey=RVOZYMPVGIVNJX-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602398   

LigandPNGBDBM50602398(CHEMBL5198935)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50602398(CHEMBL5198935)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50602398(CHEMBL5198935)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of mouse PDE9A expressed in recombinant CHO cells coexpressing soluble guanylate cyclase incubated for 6 mins by [3H]-cGMP scintillation p...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 2C9(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50602398(CHEMBL5198935)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed