BDBM50602057 CHEMBL1908842::JNJ-28312141

SMILES CN(C)CC(=O)N1CCC(CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1

InChI Key InChIKey=GUBJNPWVIUFSTR-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50602057   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50602057(CHEMBL1908842 | JNJ-28312141)
Affinity DataKd:  240nMAssay Description:Binding affinity to RIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProtein delta homolog 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50602057(CHEMBL1908842 | JNJ-28312141)
Affinity DataKd:  330nMAssay Description:Binding affinity to DLK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50602057(CHEMBL1908842 | JNJ-28312141)
Affinity DataKd:  310nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed