BDBM50601494 CHEMBL5192493

SMILES NS(=O)(=O)OC[C@@H]1C[C@H](C[C@@H]1O)n1nnc2c(N[C@H]3[C@@H](O)Cc4ccccc34)ncnc12

InChI Key InChIKey=LBCALMGKWJHMBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601494   

TargetNEDD8-activating enzyme E1 catalytic subunit(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50601494(CHEMBL5192493)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of NAE (unknown origin) mediated neddylation assessed as decrease in NEDD8-Ubcl2 adduct formation incubated for 2 hrs in presence of L-glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50601494(CHEMBL5192493)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed