BDBM50601462 CHEMBL5200275

SMILES COc1cc(ccc1Nc1ncc2C(C)OC(=O)N(c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1

InChI Key InChIKey=NRPVSNDNVFALQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601462   

TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 7nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 47nMAssay Description:Inhibition EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 7nMAssay Description:Inhibition of BTK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 47nMAssay Description:Inhibition of wildtype EGFR (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed