BDBM50601451 CHEMBL5172511

SMILES CCc1nc(C)cn1Cc1ccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1

InChI Key InChIKey=DMYYYVPFVHRQOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601451   

TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601451(CHEMBL5172511)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601451(CHEMBL5172511)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins in the presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed