BDBM50601029 CHEMBL5194823

SMILES CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(cc1)O)C(=O)OC)NC(=O)[C@H]([C@@H](CCCCO)N)O

InChI Key InChIKey=LCFWQIPNOMDXPJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601029   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601029(CHEMBL5194823)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601029(CHEMBL5194823)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using R-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601029(CHEMBL5194823)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed