BDBM50600313 CHEMBL5170703

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1)N1CCC2(CCNCC2)CC1

InChI Key InChIKey=LKGLPOBFCOFWMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600313   

TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600313(CHEMBL5170703)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of ALK C1156Y mutant (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600313(CHEMBL5170703)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50600313(CHEMBL5170703)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of wild type ALK (unknown origin) using biotinylated substrate incubated for 1 hr in the presence of ATP at Km concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed