BDBM50599663 CHEMBL5183516

SMILES Fc1cccc(CNc2nc(Nc3cccc(c3)C(=O)N[C@H]3CCCNC3)ncc2Cl)c1

InChI Key InChIKey=DUAIEVYTIKHMGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599663   

TargetBDNF/NT-3 growth factors receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599663(CHEMBL5183516)
Affinity DataIC50: 32nMAssay Description:Inhibition of TRKB (unknown origin) incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599663(CHEMBL5183516)
Affinity DataIC50: 27nMAssay Description:Inhibition of TRKA (unknown origin) incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599663(CHEMBL5183516)
Affinity DataIC50: 45nMAssay Description:Inhibition of TRKC (unknown origin) incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed