BDBM50599661 CHEMBL5189901

SMILES CNC1CCN(CC1)C(=O)c1cccc(Nc2ncc(Cl)c(NCc3cccc(F)c3)n2)c1

InChI Key InChIKey=JLVUEKVUGINUJP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599661   

TargetBDNF/NT-3 growth factors receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599661(CHEMBL5189901)
Affinity DataIC50: 67nMAssay Description:Inhibition of TRKB (unknown origin) incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599661(CHEMBL5189901)
Affinity DataIC50: 53nMAssay Description:Inhibition of TRKA (unknown origin) incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599661(CHEMBL5189901)
Affinity DataIC50: 49nMAssay Description:Inhibition of TRKC (unknown origin) incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed