BDBM50599596 CHEMBL5191668

SMILES CC(=O)Nc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1

InChI Key InChIKey=FHFQXWQTCMHWQI-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50599596   

LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 11nMAssay Description:Inhibition of PIP5Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 35nMAssay Description:Inhibition of PIP5Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PIP5Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PI4Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PI4Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599596(CHEMBL5191668)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PDK1 in human BT-474 cells assessed as reduction in AKT phosphorylation at T308 residue incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed