BDBM50599287 CHEMBL5183592

SMILES CN1C(C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12)c1ccccc1C

InChI Key InChIKey=FWEIAKDAIDQPRK-UHFFFAOYSA-N

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50599287   

TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592)
Affinity DataIC50: 652nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST2 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human NEK3 expressed in baculovirus expression system using S2 as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592)
Affinity DataKd:  240nMAssay Description:Binding affinity to wild-type human full length MST1 (M1 to F487 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599287(CHEMBL5183592)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to wild-type human partial length MST2 (D17 to E318 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed