BDBM50599022 CHEMBL5181285::US20230322715, Compound TR-FTO-37

SMILES C(NCC1(COC1)N1CCCC1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=TZTKNDPNELJLRD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599022   

TargetRNA demethylase ALKBH5(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant FTO (unknown origin) using m6A Broccoli as substrate incubated for 2 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)
Affinity DataIC50: 810nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRNA demethylase ALKBH5(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)
Affinity DataIC50: 3.30E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent