BDBM50598903 CHEMBL5189556

SMILES CCn1c(CO)nn(-c2nc(OC3CCOC3)c(cc2F)C(=O)Nc2c(F)cccc2Cl)c1=O

InChI Key InChIKey=YWSJLGZGYOJINH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50598903   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50598903(CHEMBL5189556)
Affinity DataIC50: 32nMAssay Description:Inhibition of His fused human DHODH expressed in Escherichia coli using DHO as substrate by DCIP absorbance based colorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed