BDBM50598810 CHEMBL5202826
SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3ccccc3nc12
InChI Key InChIKey=KBWZVVPCJMAFMN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50598810
Affinity DataIC50: 18nMAssay Description:Inhibition of full length Nano-luc fused EPHB3 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of WEE1 (unknown origin)More data for this Ligand-Target Pair
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair