BDBM50598715 CHEMBL5190599::US20230348487, Example LS 5-150
SMILES [H][C@]12OC[C@@H](Oc3nc(Nc4ccc(N5CCC(C5)N(C)C)c(NC(=O)C=C)c4)ncc3Cl)[C@@]1([H])OC[C@H]2O
InChI Key InChIKey=JUKPMIIZNGISMX-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50598715
Affinity DataIC50: 270nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 (866 to 1154 residues) expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 606nMAssay Description:Inhibition of GST tagged recombinant human JAK2 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of GST tagged recombinant human JAK3 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of human TYK2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 606nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.74nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair