BDBM50598711 CHEMBL5205480::US20230348487, Example LS 5-152
SMILES [H][C@]12CN(c3ccc(Nc4ncc(Cl)c(O[C@@H]5CO[C@]6([H])[C@H](O)CO[C@]56[H])n4)cc3NC(=O)C=C)[C@]([H])(CO1)C2
InChI Key InChIKey=MXJZKDHDEKITDX-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50598711
Affinity DataIC50: 190nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 (866 to 1154 residues) expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 357nMAssay Description:Inhibition of GST tagged recombinant human JAK2 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST tagged recombinant human JAK3 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of human TYK2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 357nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair