BDBM50597849 CHEMBL5205994

SMILES COc1cc(OC)c2c(c1)nc([nH]c2=O)-c1ccc(OCCOc2ccccc2C(N)=O)cc1

InChI Key InChIKey=NQBBGPWFKFVWGM-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50597849   

TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 400nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 440nMAssay Description:Inhibition of BRD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 379nMAssay Description:Inhibition of BRD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 400nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human BRD4 BD1 measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 379nMAssay Description:Inhibition of recombinant human BRD4 BD2 measured after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597849(CHEMBL5205994)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin) using NAD+ as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed