BDBM50597513 CHEMBL5178473

SMILES C[N+]1(C)CC[C@H](C1)Oc1ccc(\C=C\c2ccccc2)cc1

InChI Key InChIKey=VUPBXVOBUWSAOS-UHFFFAOYSA-M

Data  6 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50597513   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response treate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  23nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChR expressed in SH-EP1 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was evaluated for Adrenergic activity against Alpha-1 adrenergic receptor from rat aortaMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597513(CHEMBL5178473)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails
PubMed