BDBM50597504 CHEMBL5177606

SMILES [I-].C(C[N+]12CCC(CC1)CC2)Oc1ccc(\C=C\c2ccccc2)cc1

InChI Key InChIKey=CHCUKAGJWTVKND-UHFFFAOYSA-M

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50597504   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response treate...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChR expressed in SH-EP1 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50597504(CHEMBL5177606)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMed