BDBM50596985 CHEMBL5170156

SMILES Fc1cc(F)c(OCc2cccnc2F)c(c1)[C@@H]1C[C@H]1NCC(=O)N1CCC2(CCNC2)CC1

InChI Key InChIKey=AOUYVKAMPAJOPE-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596985   

TargetLysine-specific histone demethylase 1A(Human)
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596985(CHEMBL5170156)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human LSD1 assessed as demethylase activity of LSD1 using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596985(CHEMBL5170156)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human LSD1 assessed as inhibitory constant using Histone H3(1-20)K4me2 peptide as substrate incubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596985(CHEMBL5170156)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of MAO-A (unknown origin) using tyramine as substrate and measured after 10 mins by peroxidase-coupled reaction methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Riken Center For Sustainable Resource Science

Curated by ChEMBL
LigandPNGBDBM50596985(CHEMBL5170156)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of MAO-B (unknown origin) using tyramine as substrate and measured after 10 mins by peroxidase-coupled reaction methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed