BDBM50596502 CHEMBL5180328

SMILES OC(=O)Cc1ccc(Cl)c(OCCC2CCN(CC2)c2nc3ccc(Cl)cc3s2)c1

InChI Key InChIKey=FUEGDUVTXZWBMT-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50596502   

LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  603nMAssay Description:Transactivation of Gal4-fused human PPARalpha expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  987nMAssay Description:Transactivation of Gal4-fused human PPARgamma expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  19nMAssay Description:Transactivation of Gal4-fused human PPARdelta expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  49nMAssay Description:Transactivation of Gal4-fused mouse PPARdelta expressed in CHO cells co expressing pG5-Luc reporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human PPARdelta (138 to 441 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  603nMAssay Description:Agonist activity at human PPARalpha (167 to 468 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  987nMAssay Description:Agonist activity at human PPARgamma (182 to 505 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  49nMAssay Description:Agonist activity at mouse PPARdelta (138 to 441 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  1.72E+3nMAssay Description:Agonist activity at mouse PPARalpha (167 to 468 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandPNGBDBM50596502(CHEMBL5180328)
Affinity DataEC50:  744nMAssay Description:Agonist activity at mouse PPARgamma (182 to 505 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed