BDBM50596263 CHEMBL5207657

SMILES COc1ccc2ncc(F)c(\C=C/CN3CCN(CCSc4cccs4)C[C@@H]3C(O)=O)c2c1

InChI Key InChIKey=YOYJNWLSAZAWII-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596263   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Technical University of Denmark

Curated by ChEMBL
LigandPNGBDBM50596263(CHEMBL5207657)
Affinity DataEC50: <3.00E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Technical University of Denmark

Curated by ChEMBL
LigandPNGBDBM50596263(CHEMBL5207657)
Affinity DataIC50: 280nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Technical University of Denmark

Curated by ChEMBL
LigandPNGBDBM50596263(CHEMBL5207657)
Affinity DataIC50: 9.92E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed