BDBM50595877 CHEMBL5181016::US20240336629, Compound 9A

SMILES [H][C@@]12CN(CCN1c1ncc(cc1N(C=C)C2=O)C(F)(F)F)C(=O)CCOC[C@H](C)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=MICSEBMQDDZSJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595877   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50595877(CHEMBL5181016 | US20240336629, Compound 9A)
Affinity DataIC50: 0.648nMAssay Description:Inhibition of PARP7 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50595877(CHEMBL5181016 | US20240336629, Compound 9A)
Affinity DataIC50: 0.648nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent