BDBM50595810 CHEMBL5169515

SMILES C[C@@H]1CCC[C@H]1N1C(=O)C2(CC2)c2cnc(Nc3ccc(cc3)S(=O)(=O)NCCO)nc12

InChI Key InChIKey=XUCPNXUEDQNSTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595810   

LigandPNGBDBM50595810(CHEMBL5169515)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50595810(CHEMBL5169515)
Affinity DataIC50: 770nMAssay Description:Inhibition of CDK2 in human COV318 cells incubated for overnight in presence of human whole blood by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed