BDBM50595576 CHEMBL5175710

SMILES [H][C@@]12CC[C@@]([H])(C1)[C@]1(ON=C(c3cncc(c3)-c3cccc(F)c3)[C@@]21[H])C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=LSPLLQCDVBRMQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595576   

TargetCytochrome P450 11B2, mitochondrial(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595576(CHEMBL5175710)
Affinity DataIC50: 412nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Guangzhou University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595576(CHEMBL5175710)
Affinity DataIC50: 8nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed